Publications: 2018-2021


Cleto S., K. Haslinger, K.L.J. Prather, T. K. Lu. in press.  “Natural combinatorial genetics and prolific polyamine production enable siderophore diversification in Serratia plymuthica.”  BMC Biol. DOI:  10.1186/s12915-021-00971-z.

Ni, C., C.V. Dinh, K.L.J. Pratherin press. “Dynamic control of metabolism.”  Annu. Rev. Chem. Biomol. Eng.  DOI:  10.1146/annurev-chembioeng-091720-125738.

Vila-Santa, A., M.A. Islam, F.C. Ferreira, K.L.J. Prather, N.P. Mira. in press.  “Prospecting biochemical pathways to implement microbe-based production of the new-to-nature platform chemical levulinic acid.”  ACS Synth. Biol. DOI:  10.1021/acssynbio.0c00518.

Almeida, B.C., J.A. Kaczmarek, P.R. Figueiredo, K.L.J. Prather, Alexandra T. P. Carvalho. in press. “Transcription factor allosteric regulation through substrate coordination to zinc.” NAR Genom. Bioinform. DOI: 10.1093/nargab/lqab033

Ni, C., K.J. Fox, K.L.J. Pratherin press. “Substrate-Activated Expression of a Biosynthetic Pathway in Escherichia coli.”  Biotechnol. J.  DOI: 10.1002/biot.202000433.


Haslinger K., Prather K.L.J. Heterologous caffeic acid biosynthesis in Escherichia coli is affected by choice of tyrosine ammonia lyase and redox partners for bacterial Cytochrome P450. Microb Cell Fact. 19(1):26. (2020) DOI: 10.1186/s12934-020-01300-9.

Dinh C.V., Chen X., Prather K.L.J. Development of a Quorum-Sensing Based Circuit for Control of Coculture Population Composition in a Naringenin Production System. ACS Synth Biol. 9(3): 590-597 (2020) DOI: 10.1021/acssynbio.9b00451.

Prather, K.L.J. 2020 “Accelerating and expanding nature to address its greatest challenges.” Nat. Catal. 3:181–183. DOI: 10.1038/s41929-020-0422-4.

Dinh, C.V. and K. L.J. Prather. 2020. “Layered and multi-input autonomous dynamic control strategies for metabolic engineering.” Curr. Opin. Biotechnol. 65: 156-162.  DOI: 10.1016/j.copbio.2020.02.015.

Fox, K.J. and K.L.J. Prather. 2020. “Carbon catabolite repression relaxation in Escherichia coli: global and sugar-specific methods for glucose and secondary sugar co-utilization.”  Curr. Opin. Chem. Eng. 30:9-16.  DOI:  10.1016/j.coche.2020.05.005.

Marques, W.L., L.A. Anderson, L. Sandoval, M.A. Hicks, K.L.J. Prather. 2020.  “Sequence-based bioprospecting of myo-inositol oxygenase (Miox) reveals new homologues that increase glucaric acid production in Saccharomyces cerevisiae.”  Enzyme Microb. Technol. 140: 109623.  DOI:  10.1016/j.enzmictec.2020.109623

Fox, K.J. and K.L.J. Prather.  2020. “Production of D-glyceric acid from D-galacturonate in Escherichia coli.” J. Ind. Microbiol. Biotechnol. 47:1075–1081.  DOI: 10.1007/s10295-020-02323-2

Zu, Y., K.L.J. Prather, G. Stephanopoulos.  2020. “Metabolic engineering strategies to overcome precursor limitations in isoprenoid biosynthesis,” Curr. Opin. Biotechnol. 66:171-178.  DOI: 10.1016/j.copbio.2020.07.005


Dinh C.V., Prather K.L.J. Development of an autonomous and bifunctional quorum-sensing circuit for metabolic flux control in engineered Escherichia coli. Proc Natl Acad Sci U S A. :116(51):25562-25568. (2019) DOI: 10.1073/pnas.1911144116.

Kunjapur A.M., Prather K.L.J. “Development of a Vanillate Biosensor for the
Vanillin Biosynthesis Pathway in E. coli”. ACS Synth Biol 8(9):1958-1967. (2019) DOI: 10.1021/acssynbio.9b00071.

Amorim C., Silvério S.C., Prather K.L.J., Rodrigues L.R. “From lignocellulosic
residues to market: Production and commercial potential of xylooligosaccharides.”
Biotechnol Adv. pii: S0734-9750(19)30078-3 (2019) DOI: 10.1016/j.biotechadv.2019.05.003. 

Prather K.L.J. “Chemistry as biology by design.” Microb Biotechnol. 12(1):30-31 (2019). DOI: 10.1111/1751-7915.13345.

Amorim, C., S.C. Silvério, R.F S. Gonçalves, A.C. Pinheiro, S. Silva, E. Coelho, M.A. Coimbra, Prather K.L.J., L.R. Rodrigues, “Downscale fermentation for xylooligosaccharides production by recombinant Bacillus subtilis 3610.” Carbohydrate Polymers 205:176-183 (2019). DOI: 10.1016/j.carbpol.2018.09.088

Boock, J.T., A.J.E. Freedman, G.A. Tompsett, S.K. Muse, A.J. Allen, L.A. Jackson, B. Castro-Dominguez, M.T. Timko, Prather K.L.J. (co-corresponding author), J.R. Thompson, “Engineered microbial biofuel production and recovery under supercritical carbon dioxide.” Nat. Commun. 10:587 (2019). DOI: 10.1038/s41467-019-08486-6


Tompsett, G.A., J.T. Boock, C. DiSpirito, E. Stoltz, D.R. Knutson, A.G. Rivard, M.R. Overdevest, C. N. Conlon, K.L.J. Prather, J.R. Thompson, M.T. Timko, “Extraction rate and energy efficiency of supercritical carbon dioxide recovery of higher alcohols from dilute aqueous solution.” Energy Technology 6(4): 683-693 (2018). DOI: 10.1002/ente.201700626.

Amorim, C., S.C. Silvério, S.P. Silva, E. Coelho, M.A. Coimbra, K.L.J. Prather, L.R. Rodrigues, “Single-step production of arabino-xylooligosaccharides by recombinant Bacillus subtilis 3610 cultivated in brewers’ spent grain.” Carbohydrate Polymers 199:546–554 (2018). DOI: 10.1016/j.carbpol.2018.07.017.

Freedman, A.J., K.C. Peet, J.T. Boock, K. Penn, K.L.J. Prather, J.R. Thompson. 2018. “Isolation, development, and genomic analysis of Bacillus megaterium SR7 for growth and metabolite production under supercritical carbon dioxide.” Front. Microbiol. 9:2152. DOI: 10.3389/fmicb.2018.02152.

Haris S., Fang C., Bastidas-Oyanedel J.R., Prather K.J., Schmidt J.E., Thomsen M.H., “Natural antibacterial agents from arid-region pretreated lignocellulosic biomasses and extracts for the control of lactic acid bacteria in yeast fermentation.“ AMB Express 8(127) (2018). doi: 10.1186/s13568-018-0654-8.

Bonk B.M., Tarasova Y., Hicks M.A., Tidor B. and K.L.J. Prather, “Rational design of thiolase substrate specificity for metabolic engineering applications.“ Biotechnol. Bioeng. (2018). doi: 10.1002/bit.26737

de Lorenzo V., Prather K.L., Chen G.Q., O’Day E., von Kameke C., Oyarzún D.A., Hosta-Rigau L., Alsafar H., Cao C., Ji W., Okano H., Roberts R.J., Ronaghi M., Yeung K., Zhang F., Lee S.Y., “The power of synthetic biology for bioproduction, remediation and pollution control: The UN’s Sustainable Development Goals will inevitably require the application of molecular biology and biotechnology on a global scale.” EMBO Rep. 19(4): e45658 (2018). doi: 10.15252/embr.201745658

Doong S.J., Gupta A. and K.L.J. Prather, “Layered dynamic regulation for improving metabolic pathway productivity in Escherichia coli.” Proc. Natl. Acad. Sci. U S A 115(12):2964-2969 (2018). doi: 10.1073/pnas.1716920115

Anderson L.A., Islam M.A. and K.L.J. Prather, “Synthetic biology strategies for improving microbial synthesis of “green” biopolymers.” J. Biol. Chem. 293(14):5053-5061 (2018).doi: 10.1074/jbc.TM117.000368

Tan S.Z., Reisch C.R. and K.L.J. Prather, “A Robust CRISPR Interference Gene Repression System in Pseudomonas.” J. Bacteriol. 200:7: e00575-17 (2018). doi: 10.1128/JB.00575-1710.1128/JB.00575-17