2020
Haslinger K., Prather K.L.J. Heterologous caffeic acid biosynthesis in Escherichia coli is affected by choice of tyrosine ammonia lyase and redox partners for bacterial Cytochrome P450. Microb Cell Fact. 19(1):26. (2020) DOI: 10.1186/s12934-020-01300-9.
Dinh C.V., Chen X., Prather K.L.J. Development of a Quorum-Sensing Based Circuit for Control of Coculture Population Composition in a Naringenin Production System. ACS Synth Biol. 9(3): 590-597 (2020) DOI: 10.1021/acssynbio.9b00451.
Prather, K.L.J. 2020 “Accelerating and expanding nature to address its greatest challenges.” Nat. Catal. 3:181–183. DOI: 10.1038/s41929-020-0422-4.
Dinh, C.V. and K. L.J. Prather. 2020. “Layered and multi-input autonomous dynamic control strategies for metabolic engineering.” Curr. Opin. Biotechnol. 65: 156-162. DOI: 10.1016/j.copbio.2020.02.015.
Fox, K.J. and K.L.J. Prather. 2020. “Carbon catabolite repression relaxation in Escherichia coli: global and sugar-specific methods for glucose and secondary sugar co-utilization.” Curr. Opin. Chem. Eng. 30:9-16. DOI: 10.1016/j.coche.2020.05.005.
Marques, W.L., L.A. Anderson, L. Sandoval, M.A. Hicks, K.L.J. Prather. 2020. “Sequence-based bioprospecting of myo-inositol oxygenase (Miox) reveals new homologues that increase glucaric acid production in Saccharomyces cerevisiae.” Enzyme Microb. Technol. 140: 109623. DOI: 10.1016/j.enzmictec.2020.109623
Fox, K.J. and K.L.J. Prather. 2020. “Production of D-glyceric acid from D-galacturonate in Escherichia coli.” J. Ind. Microbiol. Biotechnol. 47:1075–1081. DOI: 10.1007/s10295-020-02323-2
Zu, Y., K.L.J. Prather, G. Stephanopoulos. 2020. “Metabolic engineering strategies to overcome precursor limitations in isoprenoid biosynthesis,” Curr. Opin. Biotechnol. 66:171-178. DOI: 10.1016/j.copbio.2020.07.005
2019
Dinh C.V., Prather K.L.J. Development of an autonomous and bifunctional quorum-sensing circuit for metabolic flux control in engineered Escherichia coli. Proc Natl Acad Sci U S A. :116(51):25562-25568. (2019) DOI: 10.1073/pnas.1911144116.
Kunjapur A.M., Prather K.L.J. “Development of a Vanillate Biosensor for the
Vanillin Biosynthesis Pathway in E. coli”. ACS Synth Biol 8(9):1958-1967. (2019) DOI: 10.1021/acssynbio.9b00071.
Amorim C., Silvério S.C., Prather K.L.J., Rodrigues L.R. “From lignocellulosic
residues to market: Production and commercial potential of xylooligosaccharides.”
Biotechnol Adv. pii: S0734-9750(19)30078-3 (2019) DOI: 10.1016/j.biotechadv.2019.05.003.
Prather K.L.J. “Chemistry as biology by design.” Microb Biotechnol. 12(1):30-31 (2019). DOI: 10.1111/1751-7915.13345.
Amorim, C., S.C. Silvério, R.F S. Gonçalves, A.C. Pinheiro, S. Silva, E. Coelho, M.A. Coimbra, Prather K.L.J., L.R. Rodrigues, “Downscale fermentation for xylooligosaccharides production by recombinant Bacillus subtilis 3610.” Carbohydrate Polymers 205:176-183 (2019). DOI: 10.1016/j.carbpol.2018.09.088
Boock, J.T., A.J.E. Freedman, G.A. Tompsett, S.K. Muse, A.J. Allen, L.A. Jackson, B. Castro-Dominguez, M.T. Timko, Prather K.L.J. (co-corresponding author), J.R. Thompson, “Engineered microbial biofuel production and recovery under supercritical carbon dioxide.” Nat. Commun. 10:587 (2019). DOI: 10.1038/s41467-019-08486-6
2018
Tompsett, G.A., J.T. Boock, C. DiSpirito, E. Stoltz, D.R. Knutson, A.G. Rivard, M.R. Overdevest, C. N. Conlon, K.L.J. Prather, J.R. Thompson, M.T. Timko, “Extraction rate and energy efficiency of supercritical carbon dioxide recovery of higher alcohols from dilute aqueous solution.” Energy Technology 6(4): 683-693 (2018). DOI: 10.1002/ente.201700626.
Amorim, C., S.C. Silvério, S.P. Silva, E. Coelho, M.A. Coimbra, K.L.J. Prather, L.R. Rodrigues, “Single-step production of arabino-xylooligosaccharides by recombinant Bacillus subtilis 3610 cultivated in brewers’ spent grain.” Carbohydrate Polymers 199:546–554 (2018). DOI: 10.1016/j.carbpol.2018.07.017.
Freedman, A.J., K.C. Peet, J.T. Boock, K. Penn, K.L.J. Prather, J.R. Thompson. 2018. “Isolation, development, and genomic analysis of Bacillus megaterium SR7 for growth and metabolite production under supercritical carbon dioxide.” Front. Microbiol. 9:2152. DOI: 10.3389/fmicb.2018.02152.
Haris S., Fang C., Bastidas-Oyanedel J.R., Prather K.J., Schmidt J.E., Thomsen M.H., “Natural antibacterial agents from arid-region pretreated lignocellulosic biomasses and extracts for the control of lactic acid bacteria in yeast fermentation.“ AMB Express 8(127) (2018). DOI: 10.1186/s13568-018-0654-8.
Bonk B.M., Tarasova Y., Hicks M.A., Tidor B. and K.L.J. Prather, “Rational design of thiolase substrate specificity for metabolic engineering applications.“ Biotechnol. Bioeng. (2018). DOI: 10.1002/bit.26737
de Lorenzo V., Prather K.L., Chen G.Q., O’Day E., von Kameke C., Oyarzún D.A., Hosta-Rigau L., Alsafar H., Cao C., Ji W., Okano H., Roberts R.J., Ronaghi M., Yeung K., Zhang F., Lee S.Y., “The power of synthetic biology for bioproduction, remediation and pollution control: The UN’s Sustainable Development Goals will inevitably require the application of molecular biology and biotechnology on a global scale.” EMBO Rep. 19(4): e45658 (2018). DOI: 10.15252/embr.201745658
Doong S.J., Gupta A. and K.L.J. Prather, “Layered dynamic regulation for improving metabolic pathway productivity in Escherichia coli.” Proc. Natl. Acad. Sci. U S A 115(12):2964-2969 (2018). DOI: 10.1073/pnas.1716920115
Anderson L.A., Islam M.A. and K.L.J. Prather, “Synthetic biology strategies for improving microbial synthesis of “green” biopolymers.” J. Biol. Chem. 293(14):5053-5061 (2018). DOI: 10.1074/jbc.TM117.000368
Tan S.Z., Reisch C.R. and K.L.J. Prather, “A Robust CRISPR Interference Gene Repression System in Pseudomonas.” J. Bacteriol. 200:7: e00575-17 (2018). DOI: 10.1128/JB.00575-1710.1128/JB.00575-17
2017
Haslinger, K. and K.L. J. Prather, “Pathway towards renewable chemicals.” Nat. Microbiol. 2(12):1580-1581 (2017). DOI:10.1038/s41564-017-0071-9.
Tan, S.Z. and K. L. J. Prather, “Dynamic pathway regulation: recent advances and methods of construction.” Curr. Opin. Chem. Biol. 41:28-35 (2017). DOI:10.1016/j.cbpa.2017.10.004
Reisch, C.R. and K.L. J. Prather, “Scarless Cas9 Assisted Recombineering (no-SCAR) in Escherichia coli, an easy to use system for genome editing.” Curr. Prot. Mol. Biol. 117:31.8.1-31.8.20 (2017). DOI:10.1002/cpmb.29
Khlystov, N.A., W.Y. Chan, A.M. Kunjapur, W. Shi, K.L. J. Prather and B.D. Olsen. “Material properties of the cyanobacterial reserve polymer multi-L-arginyl-poly-L-aspartate (cyanophycin).” Polymer. 109 pp: 238-245 (2017). DOI:10.1016/j.polymer.2016.11.058
Gupta, A., I.M. Brockman Reizman, C.R. Reisch and K.L. J. Prather. “Dynamic regulation of metabolic flux in engineered bacteria using a pathway-independent quorum-sensing circuit.” in press, Nat. Biotechnol. 35:273-279 (2017). DOI:10.1038/nbt.3796
2016
Sheppard, M. J.*, Kunjapur, A. M.* and K. L. J. Prather. “Modular and selective biosynthesis of gasoline-range alkanes.” Metab. Eng. 33, 28–40 (2016). *equal contribution. DOI: 10.1016/j.ymben.2015.10.010
Kunjapur, A.M., B. Cervantes, K.L.J. Prather. “Coupling carboxylic acid reductase to inorganic pyrophosphatase enhances cell-free in vitro aldehyde biosynthesis.” Biochem. Eng. J. 109: 19–27 (2016). doi: 10.1016/j.bej.2015.12.018
Tan, S.T., S. Manchester, K.L J. Prather. “Controlling central carbon metabolism for improved pathway yields in Saccharomyces cerevisiae.” ACS Syn. Biol. 5(2) pp: 116-124 (2016).. DOI:10.1021/acssynbio.5b00164
Simcikova, M., D.M. Prazeres, K.L J. Prather, G.A. Monteiro. “Towards an effective non-viral gene delivery vector.” Biotechnol. Genet. Eng. Rev. 31(1-2) pp: 82-107 (2016). DOI:10.1080/02648725.2016.1178011
Kunjapur, A.M., J.C. Hyun, K.L J. Prather. “Deregulation of S-adenosylmethionine biosynthesis and regeneration improves methylation in the E. coli de novo vanillin biosynthesis pathway.” Microb. Cell Fact. 15:61 (2016). DOI:10.1186/s12934-016-0459-x
Simcikova, M., C.P.A. Alves, L. Brito, K.L J. Prather, D.M.F. Prazeres, G.A. Monteiro. “Improvement of DNA minicircle production by optimization of the secondary structure of the 5′-UTR of ParA resolvase.” Appl. Microbiol. Biotechnol. 100(15) pp: 6725-6737 (2016). DOI:10.1007/s00253-016-7565-x
Gupta, A.L., M.A. Hicks, S.P. Manchester, K.L J. Prather. “Porting the synthetic D-glucaric acid pathway from Escherichia coli to Saccharomyces cerevisiae.” Biotechnol. J. 11(9) pp: 1201-1208 (2016). DOI:10.1002/biot.201500563
2015
Rodrigues, J.L., K.L J. Prather, L.D. Kluskens, L.R. Rodrigues. “Heterologous production of curcuminoids: a review.” Microbiol. Mol. Biol. Rev. 79 pp: 39-60 (2015). DOI:10.1128/MMBR.00031-14
Kunjapur, A. M., and K.L.J. Prather. “Microbial engineering for aldehyde synthesis.” Appl. Environ. Microbiol. 81 pp: 1892-1901. (2015). DOI:10.1128/AEM.03319-14
Brockman, I.M., and K.L.J. Prather. “Dynamic knockdown of E. coli central metabolism for redirecting fluxes of primary metabolites.” Metab. Eng. 28 pp: 104-113 (2015). DOI:10.1016/j.ymben.2014.12.005
Shiue, E., I.M. Brockman, K. L. J. Prather. “Improving product yields on D-glucose in Escherichia coli via alternative carbon sources.” Biotechnol. Bioeng.112(3) pp: 579-587 (2015). DOI:10.1002/bit.25470
Lopes, M.B., G.A.L. Gonçalves, D. Felício-Silva, K. L. J. Prather. G.A. Monteiro, D.M.F. Prazeres, C.R.C. Calado. “In-situ NIR monitoring of plasmid bioproduction processes: effect of the cultivation medium composition, the cultivation strategy, and the Escherichia coli strain.” J. Chem. Technol. Biotechnol. 90(2) pp: 255-261 (2015). DOI:10.1002/jctb.4431
Pfleger, B. F., and K. L. J. Prather. “Biological synthesis unbounded?” Nat. Biotechnol. 33, 1148–9 (2015). DOI:10.1038/nbt.3399
Tan, S. Z., Manchester, S., and K. L. J. Prather. “Controlling central carbon metabolism for improved pathway yields in Saccharomyces cerevisiae.” ACS Synth. Biol. 5(2) pp: 116-124 (2015). DOI:10.1021/acssynbio.5b00164
Boock, J. T., Gupta, A., and K. L. J. Prather. “Screening and modular design for metabolic pathway optimization.” Curr. Opin. Biotechnol. 36, 189–198 (2015).
DOI:10.1016/j.copbio.2015.08.013
Reizman, I. M. B., Stenger, A. R., Reisch, C. R., Gupta, A., Connors, N. C., and K. L. J. Prather. “Improvement of glucaric acid production in E. coli via dynamic control of metabolic fluxes.” Metab. Eng. Commun. 2, 109–116 (2015). DOI:10.1016/j.meteno.2015.09.002
Reisch, C. R., and K. L. J. Prather. “The no-SCAR (Scarless Cas9 Assisted Recombineering) system for genome editing in Escherichia coli.” Sci. Rep. 5, 15096 (2015). DOI:10.1038/srep15096
Brockman, I. M., and K. L. J. Prather. “Dynamic metabolic engineering: New strategies for developing responsive cell factories.” Biotechnol. J. 10, 1360–9 (2015). DOI:10.1002/biot.201400422
Rodrigues, J. L., Araújo, R. G., K. L. J. Prather, Kluskens, L. D. & Rodrigues, L. R. “Heterologous production of caffeic acid from tyrosine in Escherichia coli.” Enzyme Microb. Technol. 71, 36–44 (2015). DOI:10.1016/j.enzmictec.2015.01.001
Rodrigues, J.L., R. G. Araújo, K. L. J. Prather, Kluskens, L. D., Rodrigues, L. R. “Production of curcuminoids from tyrosine by a metabolically engineered Escherichia coli.” Biotechnol. J. 10(4) 599-609 (2015). DOI:10.1002/biot.201400637
Cheng, D., R. Wang, K. L. J. Prather, Chow, I.-M. Hsing. “Tackling codon usage bias for heterologous expression in Rhodobacter sphaeroides by supplementation of rare tRNAs.” Enzyme Microbiol. Technol. 72:25-34 (2015). DOI:10.1016/j.enzmictec.2015.02.003